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Friday, November 20, 2020 | History

6 edition of post-imperative negative variation in schizophrenic patients and healthy subjects found in the catalog.

post-imperative negative variation in schizophrenic patients and healthy subjects

Christoph Klein.

by Klein, Christoph Ph. D.

  • 154 Want to read
  • 32 Currently reading

Published by P. Lang in Frankfurt am Main, New York .
Written in English

    Subjects:
  • Schizophrenia -- Physiological aspects.,
  • Slow potentials (Electrophysiology),
  • Evoked potentials (Electrophysiology),
  • Schizophrenia -- physiopathology.,
  • Contingent Negative Variation -- physiology.

  • Edition Notes

    Includes bibliographical references (p. 293-356).

    SeriesPsychophysiologie in Labor und Feld,, Bd. 3
    Classifications
    LC ClassificationsRC514 .K588 1997
    The Physical Object
    Pagination386 p. :
    Number of Pages386
    ID Numbers
    Open LibraryOL1012731M
    ISBN 103631310781, 0820432334
    LC Control Number96053386

    The Evolution of Schizophrenia Research and TreatmentAuthor: James P. Kelleher. Schizophrenia is a mental health disorder that is characterised by distorted perceptions and behaviours. Symptoms of the condition are divided into two categories: positive and negative. Positive symptoms cause an excess of cognitive function and include delusions and hallucinations. Negative symptoms suppress normal function and includeFile Size: KB. High-functioning schizophrenia is when one can hide the illness when in public but exposing their negative traits behind closed doors. Schizophrenia is a kind of mental condition in which there is a total or partial disconnect between what a person sees and hears and what is real. Most people with schizophrenia can hear, see and feel. People with schizophrenia can experience both positive and negative doesn't mean that there are "good" versus "bad" symptoms. Positive symptoms are behaviors that appear in surplus in people with schizophrenia and are typically not found in otherwise healthy : Adrian Preda, MD.


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post-imperative negative variation in schizophrenic patients and healthy subjects by Klein, Christoph Ph. D. Download PDF EPUB FB2

The Post-Imperative Negative Variation (PINV) is an event-related brain potential that has scarcely been investigated experimentally in schizophrenic : Paperback.

The post-imperative negative variation in schizophrenic patients and healthy subjects: Christoph Klein. ELSEVIER Schizophrenia Research 21 () SCHIZOPHRENIA RESEARCH Contingent negative variation (CNV) and determinants of the post-imperative negative variation (PINV) in schizophrenic patients and healthy controls1 Christoph Klein *, Brigitte Rockstroh, Rudolf Cohen, Patrick Berg Department of Psychology, University of Konstanz, Konstanz, Germany Received 27 Cited by: Objective: The goal of this placebo-controlled study was to evaluate the efficacy and.

safety of low doses of amisulpride, an atypical antipsychotic of the benzamide class with. high affinity for D2and D3dopamine receptors, in the treatment of schizophrenic patients. OBJECTIVE: Three hypotheses were tested: 1) schizophrenic patients would report more impairments on a self-rating scale for negative symptoms than normal subjects and attribute higher levels of distress to these impairments, 2) schizophrenic patients would report fewer impairments than patients with a depressive disorder and attribute lower levels of distress to these impairments, and 3 Cited by: Negative Symptom Schizophrenic Patient Positive Symptom Hierarchical Theory Marked Degree These keywords were added by machine and not by the authors.

This process is experimental and the keywords may be updated as the learning algorithm by: 1. This study was concerned with the relationship between attentional and information-processing deficits and positive vs.

negative symptoms in schizophrenia. Sixteen schizophrenic patients, rated for extent of positive and negative symptomatology, 17 depressed patients, and 31 normal control subjects were tested on a measure of distractibility Cited by: Negative symptoms (such as amotivation and diminished expression) associated with schizophrenia are a major health concern.

Adequate treatment would mean important progress with respect to quality. Marked negative symptoms were found to occur in a subgroup of schizophrenic subjects at followup, but were infrequent in depressed subjects. Educational difficulties and poor social functioning before initial hospitalization were associated with later negative symptoms at followup for schizophrenic by: Reduced CNV and continued negativity after S2 (post-imperative negative variation, PINV) have been repeatedly found in schizophrenic patients and have been interpreted as a deficit in attentional.

Negative symptoms in schizophrenia: A study in a large clinical sample of patients using a novel automated method 90% of individuals with schizophrenia have some negative sympt 26 and. In schizophrenia patients, the response difference between the first and second stimulus is typically reduced (Patterson et al., ).

Surprisingly, only few studies have linked the sensory gating deficit in electrophysiological data to positive or negative symptoms in schizophrenia (Potter et al., ; Keshavan et al., ).Cited by:   Distinction between true post-imperative negative variation in schizophrenic patients and healthy subjects book and depressive symptoms in schizophrenia is difficult.

In the present study we seek to establish the psychological profile of depression-prone schizophrenic by: The negative symptoms have been described in association with schizophrenia since the early days of it being recognized as an entity.

However, their elusive nature kept them unacknowledged until. The current study thus aims to evaluate the performance of combining MMN with neuropsychological tests to differentiate schizophrenia patients from healthy subjects in a population of Han Chinese Ethnicity.

The pattern of discriminating schizophrenia patients from healthy subjects by MMN is related to the types of deviant stimuli and by: VOL. 11, NO. 3, Positive and Negative Schizophrenic Symptoms, Attention, and Information Processing by Barbara A.

Cornblatt, Mark F. Lenzenweger, Robert H. Negative and positive symptoms were determined for 46 drug-free patients who met Research Diagnostic Criteria (RDC) and/or Feighner criteria for schizophrenia. A modified version of the Scale for the Assessment of Negative Symptoms (SANS) was completed for each patient based on items from the Schedule for Affective Disorders and Schizophrenia Cited by: Negative Versus Positive Schizophrenia.

Editors (view affiliations) Andreas Marneros; Long-Term Outcome of Patients with a Positive Initial Episode Versus Patients with a Negative Initial Episode Pages The Concept of Positive and Negative Schizophrenia in Child and Adolescent Psychiatry.

Remschmidt, M. Martin, E. Schulz, C. Defining the Deficit Syndrome and Persistent Negative Symptoms. Kraepelin's “avolitional syndrome” is the foundation for the concept of the deficit syndrome in schizophrenia. 1 InCarpenter and colleagues proposed a schizophrenia subtype defined by negative symptoms primary (or idiopathic) to the illness and not secondary to other manifestations of the illness or its Cited by: METHOD: A self-rating scale for negative symptoms was administered to 86 patients with schizophrenia, 20 patients with a depressive disorder, and 33 normal subjects.

The scale items were derived from the Scale for the Assessment of Negative Symptoms (SANS). Two psychiatrists also rated all of the patients on the by: Introduction. Negative symptoms, which include amotivation, a flattening of emotional responses, a reduction in speech and activity, and social withdrawal,1contribute to much of the disability associated with schizophrenia.2These symptoms are also associated with poor psychosocial functioning3and a reduced likelihood of remission.4–9The aetiology and pathophysiology of negative symptoms are unknown, and there are no effective treatments Cited by:   A review of Clozapine's impact on negative symptoms among refractory patients, for example, demonstrated benefits for negative symptoms restricted to anhedonia.

16 By contrast, in a study of Olanzapine among non-refractory patients, benefits for negative symptoms were observed in all factors except anhedonia and asociality. 17 Although methodological factors may explain some of the discrepancies, factor analyses of two of the most widely used instruments measuring negative symptoms Cited by: Response to haloperidol in schizophrenia The aims of this paper is to quantify response of negative symptomatology to haloperidol in schizophrenic patients with acute exacerbation, to identify which negative symptoms respond to treatment, and to identify as well possible associated socio-demographic and clinical by: C.

Klein, B. Rockstroh, R. Cohen, P. BergContingent negative variation (CNV) and determinants of the post-imperative negative variation (PINV) in schizophrenic patients and healthy controls Schizophr Res, 21 (), pp. Cited by: 1.

PSYCHIATRISTS from a variety of theoretical perspectives, including Kraepelin 1 and Bleuler, 2 have noted that family members of patients with schizophrenia often have odd personality features, including social isolation, poor interpersonal relationships, unusual thought content, and odd speech.

These traits were combined into our current concept of schizotypy by Spitzer et al in DSM Cited by: Second, we trained the support vector machine (SVM) to obtain a classification model that classified 20 positive and 11 negative schizophrenic patients. The results showed that 84% subjects were correctly classified.

We demonstrated that the united method of VBM and SVM would provide a useful tool for clinical diagnostic by: 2. The schizophrenic’s essential and paramount battle may be to ameliorate the effects of stigma, a consequence of implicit societal attitudes that are a reaction to the schizophrenic’s hapless.

Some studies have found that depressive symptoms in patients with schizophrenia may be secondary to negative symptoms, medications, or neuro­leptic-induced movement disorders, whereas others have reported that in patients with chronic schizophrenia (3–7) and even first-episode schizophrenia, depressive symptoms may be a core component of various stages of this by:   Healthy controls (A), patients with schizophrenia (B), and significantly different activation between groups (subtraction of SZ-CO) (C) are shown.

The time series plots in the middle column show activation associated with true memory maintenance (red lines) relative to the baseline activities (blue line). This study subgroups schizophrenic patients based on symptoms assessed on admission and examines the validity of the subgrouping using follow-up data and other clinical outcome variables.

Schizophrenic patients (n =) from consecutive admission received ratings on the positive and negative syndrome scale (PANSS) on admission and during a 1 Cited by:   Other models using the positive/negative symptom dichotomy ensued, such as, type I and type II schizophrenia4,5 and positive and negative schizophrenia.6,7 All these constructs were attempts to explain the heterogeneity of schizophrenia.

Negative symptoms account for much of the long-term morbidity and poor functional outcome of patients with Cited by: Negative symptoms are an intrinsic component of schizophrenic psychopathology, and they can also be caused by secondary factors.

6,7 Distinguishing between primary and secondary causes of negative symptoms can help you select appropriate treatment in specific clinical situations. Negative symptoms are the major contributor to low function levels and debilitation in most patients with schizophrenia.

Poorly motivated patients cannot function adequately at school or work. Relationships with family and friends decay in the face of unresponsive affect and inattention to social cues. Pimavanserin – Schizophrenia Negative Symptoms Innovation Pimavanserin is a proprietary small molecule that we have advanced to Phase 2 development for negative symptoms of schizophrenia.

Pimavanserin is a selective serotonin inverse agonist (SSIA) preferentially targeting 5-HT2A receptors. Its distinct mechanism of action targets serotonergic 5-HT2A receptors while avoiding activity at.

Objectives To identify negative symptoms in the clinical records of a large sample of patients with schizophrenia using natural language processing and assess their relationship with clinical outcomes.

Design Observational study using an anonymised electronic health record case register. Setting South London and Maudsley NHS Trust (SLaM), a large provider of inpatient and community Cited by: VOL. 10, NO. 3, Negative and Positive Symptoms in Schizophrenia and Depression: A Followup by Michael F.

PogueGeile and Martin Harrow Abstract Negative and positive symptoms were investigated in a sample of 72 young schizophrenic and depressed patients at followup approximately 1V4 years after hospital discharge. Flat affect, poverty of. Negative symptoms of schizophrenia are associated with poor functional outcome and place a substantial burden on people with this disorder, their families, and health-care systems.

We summarise the evolution of the conceptualisation of negative symptoms, the most important findings, and the remaining open questions. Several studies have shown that negative symptoms might be primary to Cited by: Giancarlo Cerveri, 1 Camilla Gesi, 2 Claudio Mencacci 2 1 Mental Health Department, ASST Lodi, Lodi, Italy; 2 Mental Health Department, ASST Fatebenefratelli-Sacco, Milan, Italy Abstract: The clinical presentation of schizophrenia encompasses symptoms divided into three dimensions: positive, negative, and cognitive.

Negative symptoms (NS), in particular, have a major impact on the quality of Cited by: 2. Negative Schizophrenic Symptoms: Pathophysiology and Clinical Implications (Progress in Psychiatry): Medicine & Health Science Books @ Schizophrenia is a mental illness characterized by relapsing episodes of psychosis.

Major symptoms include hallucinations (often hearing voices), delusions (having beliefs not shared by others), and disorganized thinking. Other symptoms include social withdrawal, decreased emotional expression, and lack of motivation. Symptoms typically come on gradually, begin in young adulthood, and in many Complications: Suicide, heart disease, lifestyle diseases.

Subjects and sample. The criteria for inclusion in the study were a diagnosis of schizophrenia or schizoaffective disorder according to DSM-IV criteria (), age between 18 and 45 years, enrollment for mental health services in a community outpatient facility (Spokane Mental Health), residence with the family of origin or in regular contact with the family, patient and family consent to Cited by:   The article on lifestyle and physical health in schizophrenia is a brilliant write up which indeed is an eye psychiatrists have a major contribution towards the deterioration of the physical health of patients through the prescribing of antipsychotic cannot andshould not absolve ourselves of the responsibility towards Cited by:   Schizophrenia Treatment - Psychosocial Interventions (Continued) Cognitive behavioral therapy (CBT): This type of intervention can help patients with schizophrenia change disruptive or destructive thought patterns, and enable them to function more optimally.

It can help patients "test" the reality of their thoughts to identify hallucinations or.